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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDX
All Species:
34.85
Human Site:
T545
Identified Species:
85.19
UniProt:
P35241
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35241
NP_002897.1
583
68564
T545
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Chimpanzee
Pan troglodytes
XP_522176
765
86955
T727
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Rhesus Macaque
Macaca mulatta
XP_001104955
604
71016
T545
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Dog
Lupus familis
XP_536581
583
68531
T545
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Cat
Felis silvestris
Mouse
Mus musculus
P26043
583
68582
T545
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Rat
Rattus norvegicus
O35763
577
67720
T539
A
R
D
E
S
K
K
T
T
N
D
M
I
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PU45
583
68536
T545
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Frog
Xenopus laevis
NP_001090034
580
68116
T542
A
R
D
D
T
K
K
T
T
N
D
L
L
H
A
Zebra Danio
Brachydanio rerio
O57457
619
70690
I580
T
Q
G
D
P
I
K
I
R
H
S
H
S
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46150
578
68123
T540
S
R
D
E
T
K
E
T
A
N
D
K
I
H
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.2
96.3
99.3
N.A.
98.2
80.6
N.A.
N.A.
97.7
81.4
21.9
N.A.
58.8
N.A.
N.A.
N.A.
Protein Similarity:
100
76.2
96.5
100
N.A.
99.6
89.5
N.A.
N.A.
99.6
90.3
42.4
N.A.
75.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
N.A.
100
80
6.6
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
100
93.3
33.3
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
0
0
0
0
0
0
10
0
0
0
0
0
80
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
90
20
0
0
0
0
0
0
90
0
0
0
0
% D
% Glu:
0
0
0
80
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
10
0
90
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
90
90
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
60
0
0
0
0
0
0
% Q
% Arg:
0
90
0
0
0
0
0
0
10
0
0
0
0
0
20
% R
% Ser:
10
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% S
% Thr:
10
0
0
0
80
0
0
90
20
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _